Tiba Medical Collaboration Announced

Tiba Medical and Spaulding Clinical Research Team Up to Bring Blood Pressure Monnitoring to Phase I Cardiac Safety Clinical Trials

July 2, 2009 ‐ Milwaukee, WI Tiba Medical and Spaulding Clinical Research announced today an important collaboration for supporting Phase I cardiac safety clinical trials.

As part of this strategic agreement, Spaulding Clinical Research has integrated Tiba Medical’s Ambulo 2400 ambulatory blood pressure monitoring (ABPM) systems into its suite of offerings. In this way, clinical trials that need to review blood pressure as a cardiac safety biomarker can now obtain, acquire, analyze, and report findings seamlessly. The ambulatory device and related software will greatly simplify and improve the frequent acquisition of blood pressure data in varying activity states. The completed solution will allow pharmaceutical companies and their Clinical Research Organization (CRO) partners to accomplish the following objectives:

Mortara Partnership Announced

Spaulding Clinical Research and Mortara Instrument Announce Collaboration to Develop Advanced ECG Technologies for Phase I Cardiac Safety Studies

Collaboration Includes Development and Validation of Automatic ECG Analysis Tools for use in Clinical Trials

Milwaukee, WI - March 9, 2009 —Spaulding Clinical Research, a next generation Clinical Research Unit designed from the ground up for Cardiac Safety studies, announced today a strategic agreement with Mortara Instrument. As part of the agreement, both companies shall collaborate on the design, implementation and verification of new ECG acquisition, analysis and report generating technologies for clinical testing of new drugs.

OBS Partnership Announced

Partnership Formed to Offer Next Generation Technologies and Services for Better Drug Cardiac Safety

Washington, DC - January 12, 2009 - At CBI’s 3rd Annual Cardiac Safety Summit, Spaulding Clinical and OBS Medical announced that they have entered into a strategic relationship to promote an integrated suite of technologies and services for improving cardiac safety.